Begin by bringing a large pot of salted water to a vigorous boil over high heat. Once boiling, add the penne pasta and cook for about 8-10 minutes until it's just shy of al dente. Reserve 1 cup of the pasta water, then carefully drain the pasta in a colander and set it aside while you prepare the sauce.

In a spacious skillet, heat 2 tablespoons of olive oil over medium heat until shimmering. Add the diced yellow onion and sauté for around 5 minutes until it turns soft and translucent, stirring occasionally.

Once the onions are ready, increase the heat slightly and add the ground turkey to the skillet. Use a wooden spoon to break it apart and cook for 6-8 minutes until it's beautifully browned. Season the turkey with salt, pepper, and Italian seasoning, then stir in the minced garlic, cooking for an additional minute.

Sprinkle all-purpose flour evenly over the turkey mixture, stirring it in for about 1 minute. Gradually pour in the chicken broth and tomato sauce, stirring continuously until the mixture begins to thicken, which should take about 3-5 minutes.

Gently fold the cooked penne pasta into the turkey sauce, ensuring every piece is well-coated. Pour in the half-and-half for an extra creamy texture, and season as needed with additional salt and pepper.

Reduce the skillet heat to low and sprinkle half of the mozzarella and cheddar cheese into the pasta mixture. Stir well until the cheese melts and incorporates into the sauce, then top with the remaining cheese and cover the skillet for a minute.

Remove the skillet from heat and garnish your Gordon Ramsay Ground Turkey Pasta with freshly chopped parsley and a sprinkle of red chili flakes for an optional kick. Serve immediately while hot.